A novel fusion protein consisting of anti-ANGPTL3 antibody and interleukin-22 ameliorates diabetic nephropathy in mice

INTRODUCTION: The pathogenic mechanisms of diabetic nephropathy (DN) include podocyte injury, inflammatory responses and metabolic disorders. Although the antagonism of Angiopoietin-like protein 3 (ANGPTL3) can alleviate proteinuria symptoms by inhibiting the activation of integrin αvβ3 on the surfa...

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Detalles Bibliográficos
Autores principales: Ma, Qianqian, Hu, Xiaozhi, Liu, Fangyu, Cao, Zhonglian, Han, Lei, Zhou, Kaicheng, Bai, Yu, Zhang, Yuting, Nan, Yanyang, Lv, Qianying, Rao, Jia, Wu, Tao, Yang, Xue, He, Haidong, Ju, Dianwen, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760875/
https://www.ncbi.nlm.nih.gov/pubmed/36544775
http://dx.doi.org/10.3389/fimmu.2022.1011442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9760875/
https://www.ncbi.nlm.nih.gov/pubmed/36544775
http://dx.doi.org/10.3389/fimmu.2022.1011442

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