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MiR-4291 stabilized the vulnerable atherosclerotic plaques by degrading the MAPK1/ERK2 in ApoE(-/-) mice

BACKGROUND: This study sought to explore the mechanism of action of the micro ribonucleic acid (miR)-4291 in stabilizing atherosclerotic (AS) plaques. METHODS: An AS model of apolipoprotein E-deficient (ApoE(-/-)) mice fed a high-fat diet (HFD) was established. Oxidized low-density lipoprotein (ox-L...

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Detalles Bibliográficos
Autores principales: Jin, Yaqiong, Lu, Jingchao, Liu, Fan, Yang, Xiuchun, Chen, Fei, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761127/
https://www.ncbi.nlm.nih.gov/pubmed/36544668
http://dx.doi.org/10.21037/atm-22-5241