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MiR-4291 stabilized the vulnerable atherosclerotic plaques by degrading the MAPK1/ERK2 in ApoE(-/-) mice
BACKGROUND: This study sought to explore the mechanism of action of the micro ribonucleic acid (miR)-4291 in stabilizing atherosclerotic (AS) plaques. METHODS: An AS model of apolipoprotein E-deficient (ApoE(-/-)) mice fed a high-fat diet (HFD) was established. Oxidized low-density lipoprotein (ox-L...
Autores principales: | Jin, Yaqiong, Lu, Jingchao, Liu, Fan, Yang, Xiuchun, Chen, Fei, Zhang, Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761127/ https://www.ncbi.nlm.nih.gov/pubmed/36544668 http://dx.doi.org/10.21037/atm-22-5241 |
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