TGR5 overexpression mediated by the inhibition of transcription factor SOX9 protects against hypoxia-/reoxygenation-induced injury in hippocampal neurons by activating Nrf2/HO-1 signaling

BACKGROUND: Cerebral ischemia/reperfusion (CI/R) injury is a destructive cerebrovascular disease associated with long-term disability and high mortality rates. TGR5 has been discovered in multiple human and animal tissues and to modulate a variety of physiological processes. The current study sought...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Hong, Chen, Yaoqi, Liu, Yalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761130/
https://www.ncbi.nlm.nih.gov/pubmed/36544646
http://dx.doi.org/10.21037/atm-22-5225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761130/
https://www.ncbi.nlm.nih.gov/pubmed/36544646
http://dx.doi.org/10.21037/atm-22-5225

Ejemplares similares