MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis

BACKGROUND: With uncontrolled inflammatory progression, acute pancreatitis (AP) can progress to severe acute pancreatitis (SAP). Inflammation and parenchymal cell death are key pathologic responses of AP. Toll-like receptor 4 (TLR4) plays a pro-inflammatory role in AP. Myeloid differentiation primar...

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Detalles Bibliográficos
Autores principales: Yang, Du-Jiang, Wang, Xiao-Dong, Fu, Xiao-Ying, Lu, Hui-Min, Zhou, Zong-Guang, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761135/
https://www.ncbi.nlm.nih.gov/pubmed/36544673
http://dx.doi.org/10.21037/atm-22-5134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761135/
https://www.ncbi.nlm.nih.gov/pubmed/36544673
http://dx.doi.org/10.21037/atm-22-5134

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