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Multi-omics profiling identifies C1QA/B(+) macrophages with multiple immune checkpoints associated with esophageal squamous cell carcinoma (ESCC) liver metastasis

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a highly lethal malignant tumor lacking effective treatments; 20% of ESCC patients develop liver metastasis with an extremely short survival time of ≈5 months. The tumor microenvironment (TME) plays a crucial role in tumor homeostasis, but the...

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Detalles Bibliográficos
Autores principales: Zheng, Fei, Zhang, Wei, Yang, Baihua, Chen, Mingqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761157/
https://www.ncbi.nlm.nih.gov/pubmed/36544679
http://dx.doi.org/10.21037/atm-22-5351