IgE glycans promote anti-IgE IgG autoantibodies that facilitate IgE serum clearance via Fc Receptors

BACKGROUND: Recent studies have shown that IgE glycosylation significantly impacts the ability of IgE to bind to its high-affinity receptor FcεRI and exert effector functions. We have recently demonstrated that immunizing mice with IgE in a complex with an allergen leads to a protective, glycan-depe...

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Detalles Bibliográficos
Autores principales: Plattner, Kevin, Gharailoo, Zahra, Zinkhan, Simon, Engeroff, Paul, Bachmann, Martin F., Vogel, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761184/
https://www.ncbi.nlm.nih.gov/pubmed/36544773
http://dx.doi.org/10.3389/fimmu.2022.1069100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761184/
https://www.ncbi.nlm.nih.gov/pubmed/36544773
http://dx.doi.org/10.3389/fimmu.2022.1069100

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