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Lysyl hydroxylase 3–mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV)

Collagens are the most abundant proteins in the body and among the most biosynthetically complex. A molecular ensemble of over 20 endoplasmic reticulum resident proteins participates in collagen biosynthesis and contributes to heterogeneous post-translational modifications. Pathogenic variants in ge...

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Detalles Bibliográficos
Autores principales: Ishikawa, Yoshihiro, Taga, Yuki, Coste, Thibault, Tufa, Sara F., Keene, Douglas R., Mizuno, Kazunori, Tournier-Lasserve, Elisabeth, Gould, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761383/
https://www.ncbi.nlm.nih.gov/pubmed/36403858
http://dx.doi.org/10.1016/j.jbc.2022.102713