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Lysyl hydroxylase 3–mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV)

Collagens are the most abundant proteins in the body and among the most biosynthetically complex. A molecular ensemble of over 20 endoplasmic reticulum resident proteins participates in collagen biosynthesis and contributes to heterogeneous post-translational modifications. Pathogenic variants in ge...

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Detalles Bibliográficos
Autores principales:	Ishikawa, Yoshihiro, Taga, Yuki, Coste, Thibault, Tufa, Sara F., Keene, Douglas R., Mizuno, Kazunori, Tournier-Lasserve, Elisabeth, Gould, Douglas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761383/ https://www.ncbi.nlm.nih.gov/pubmed/36403858 http://dx.doi.org/10.1016/j.jbc.2022.102713

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