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Single-cell profiling of mouse and primate ovaries identifies high levels of EGFR for stromal cells in ovarian aging

Increased ovarian fibrosis and an expanded stromal cell compartment are the main characteristics of aging ovaries. However, the molecular mechanisms and the key factor of stromal cells underlying ovarian aging remain unclear. Here, we explored single-cell transcriptomic data of ovaries from the adul...

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Detalles Bibliográficos
Autores principales: Wei, Ye, Yu, Ruidi, Cheng, Sheng, Zhou, Ping, Mo, Shaomei, He, Chao, Deng, Chang, Wu, Peng, Liu, He, Cao, Canhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761475/
https://www.ncbi.nlm.nih.gov/pubmed/36570672
http://dx.doi.org/10.1016/j.omtn.2022.11.020