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Targeting Na-H exchanger 1 overcomes nuclear factor kappa B-mediated tumor resistance to radiotherapy

Intrinsic or acquired radioresistance often limits the efficacy of radiation therapy (RT), thereby leading to local control failure. Cancerous cells have abnormal pH dynamics due to high metabolic demands, but it is unclear how pH dynamics contribute to radioresistance. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Son, Arang, Kang, Seoyeong, Choi, Suha, Shin, Sung-Won, Kim, Yeeun, Kim, Wankyu, Choi, Changhoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761853/
https://www.ncbi.nlm.nih.gov/pubmed/36508876
http://dx.doi.org/10.1016/j.neo.2022.100862