Capsaicin-Induced Endocytosis of Endogenous Presynaptic Ca(V)2.2 in DRG-Spinal Cord Co-Cultures Inhibits Presynaptic Function

The N-type calcium channel, Ca(V)2.2 is key to neurotransmission from the primary afferent terminals of dorsal root ganglion (DRG) neurons to their postsynaptic targets in the spinal cord. In this study, we have utilized Ca(V)2.2_HA knock-in mice, because the exofacial epitope tag in Ca(V)2.2_HA ena...

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Detalles Bibliográficos
Autores principales: Ramgoolam, Krishma H, Dolphin, Annette C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761886/
https://www.ncbi.nlm.nih.gov/pubmed/36540890
http://dx.doi.org/10.1093/function/zqac058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761886/
https://www.ncbi.nlm.nih.gov/pubmed/36540890
http://dx.doi.org/10.1093/function/zqac058

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