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Capsaicin-Induced Endocytosis of Endogenous Presynaptic Ca(V)2.2 in DRG-Spinal Cord Co-Cultures Inhibits Presynaptic Function
The N-type calcium channel, Ca(V)2.2 is key to neurotransmission from the primary afferent terminals of dorsal root ganglion (DRG) neurons to their postsynaptic targets in the spinal cord. In this study, we have utilized Ca(V)2.2_HA knock-in mice, because the exofacial epitope tag in Ca(V)2.2_HA ena...
Autores principales: | Ramgoolam, Krishma H, Dolphin, Annette C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761886/ https://www.ncbi.nlm.nih.gov/pubmed/36540890 http://dx.doi.org/10.1093/function/zqac058 |
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