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Slowing Heart Rate Protects Against Pathological Cardiac Hypertrophy

We aimed to determine the pathophysiological impact of heart rate (HR) slowing on cardiac function. We have recently developed a murine model in which it is possible to conditionally delete the stimulatory heterotrimeric G-protein (Gα(s)) in the sinoatrial (SA) node after the addition of tamoxifen u...

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Detalles Bibliográficos
Autores principales: Sebastian, Sonia, Weinstein, Lee S, Ludwig, Andreas, Munroe, Patricia, Tinker, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761894/
https://www.ncbi.nlm.nih.gov/pubmed/36540889
http://dx.doi.org/10.1093/function/zqac055