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Development of a thiostrepton-free system for stable production of PLD in Streptomyces lividans SBT5

BACKGROUND: Phospholipase D (PLD) is highly valuable in the food and medicine industries, where it is used to convert low-cost phosphatidylcholine into high-value phospholipids (PLs). Despite being overexpressed in Streptomyces, PLD production requires expensive thiostrepton feeding during fermentat...

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Detalles Bibliográficos
Autores principales: Wang, Juntan, Zhu, Haihua, Shang, Huiyi, Guo, Bishan, Zhang, Mengxue, Wang, Fayun, Zhang, Lipan, Xu, Jun, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761944/
https://www.ncbi.nlm.nih.gov/pubmed/36529749
http://dx.doi.org/10.1186/s12934-022-01992-1