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Rapid Generation of Circulating and Mucosal Decoy Human ACE2 using mRNA Nanotherapeutics for the Potential Treatment of SARS‐CoV‐2

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can cause lethal pulmonary damage in humans. It contains spike proteins on its envelope that bind to human angiotensin‐converting enzyme 2 (hACE2) expressed on airway cells, enabling entry of the virus, and causing infection. The soluble f...

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Detalles Bibliográficos
Autores principales: Kim, Jeonghwan, Jozic, Antony, Mukherjee, Anindit, Nelson, Dylan, Chiem, Kevin, Khan, Md Siddiqur Rahman, Torrelles, Jordi B., Martinez‐Sobrido, Luis, Sahay, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762296/
https://www.ncbi.nlm.nih.gov/pubmed/36216580
http://dx.doi.org/10.1002/advs.202202556