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Structural studies of the spliceosome: Bridging the gaps
The spliceosome is a multi-megadalton RNA–protein complex responsible for the removal of non-coding introns from pre-mRNAs. Due to its complexity and dynamic nature, it has proven to be a very challenging target for structural studies. Developments in single particle cryo-EM have overcome these prev...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762485/ https://www.ncbi.nlm.nih.gov/pubmed/36116369 http://dx.doi.org/10.1016/j.sbi.2022.102461 |