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IRF2 is required for development and functional maturation of human NK cells

Natural killer (NK) cells are cytotoxic and cytokine-producing lymphocytes that play an important role in the first line of defense against malignant or virus-infected cells. A better understanding of the transcriptional regulation of human NK cell differentiation is crucial to improve the efficacy...

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Detalles Bibliográficos
Autores principales: Persyn, Eva, Wahlen, Sigrid, Kiekens, Laura, Van Loocke, Wouter, Siwe, Hannah, Van Ammel, Els, De Vos, Zenzi, Van Nieuwerburgh, Filip, Matthys, Patrick, Taghon, Tom, Vandekerckhove, Bart, Van Vlierberghe, Pieter, Leclercq, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762550/
https://www.ncbi.nlm.nih.gov/pubmed/36544762
http://dx.doi.org/10.3389/fimmu.2022.1038821