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The novel subclusters based on cancer-associated fibroblast for pancreatic adenocarcinoma

INTRODUCTION: Pancreatic adenocarcinoma (PAAD) is a fatal disease characterized by promoting connective tissue proliferation in the stroma. Activated cancer-associated fibroblasts (CAFs) play a key role in fibrogenesis in PAAD. CAF-based tumor typing of PAAD has not been explored. METHODS: We extrac...

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Detalles Bibliográficos
Autores principales: Zhao, Guojie, Wang, Changjing, Jiao, Jian, Zhang, Wei, Yang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762551/
https://www.ncbi.nlm.nih.gov/pubmed/36544710
http://dx.doi.org/10.3389/fonc.2022.1045477