Cargando…

A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells

Key targets of both the therapeutic and abused properties of opioids are μ-opioid receptors (MORs). Despite years of research investigating the biochemistry and signal transduction pathways associated with MOR activation, we do not fully understand the cellular mechanisms underlying opioid addiction...

Descripción completa

Detalles Bibliográficos
Autores principales: Mengaziol, Juliet, Dunn, Amelia D., Salimando, Gregory, Wooldridge, Lisa, Crues-Muncunill, Jordi, Eacret, Darrell, Chen, Chongguang, Bland, Kathryn, Liu- Chen, Lee-Yuan, Ehrlich, Michelle E., Corder, Gregory, Blendy, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762562/
https://www.ncbi.nlm.nih.gov/pubmed/36534642
http://dx.doi.org/10.1371/journal.pone.0270317