High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire

Antibodies targeting the human malaria parasite Plasmodium falciparum circumsporozoite protein (PfCSP) can prevent infection and disease. PfCSP contains multiple central repeating NANP motifs; some of the most potent anti-infective antibodies against malaria bind to these repeats. Multiple antibodie...

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Detalles Bibliográficos
Autores principales: Kucharska, Iga, Binter, Špela, Murugan, Rajagopal, Scally, Stephen W., Ludwig, Julia, Prieto, Katherine, Thai, Elaine, Costa, Giulia, Li, Kan, Horn, Gillian Q., Flores-Garcia, Yevel, Bosch, Alexandre, Sicard, Taylor, Rubinstein, John L., Zavala, Fidel, Dennison, S. Moses, Tomaras, Georgia D., Levashina, Elena A., Kellam, Paul, Wardemann, Hedda, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762590/
https://www.ncbi.nlm.nih.gov/pubmed/36441829
http://dx.doi.org/10.1371/journal.ppat.1010999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762590/
https://www.ncbi.nlm.nih.gov/pubmed/36441829
http://dx.doi.org/10.1371/journal.ppat.1010999

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