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Synthesis of water-soluble porphyrin with tyrosine fragments and study of its interaction with S-protein of SARS-CoV-2

The multistage purposeful synthesis of 5,15-bis(4′-l-N-tyrosinylamidophenyl)-10,20-bis(N-methylpyridin-3′-yl)porphine diiodide was carried out, and the optimum synthesis conditions were determined. 5,15-Bis(4′-nitrophenyl)-10,20-bis(pyridin-3′-yl)porphine served as the starting porphyrin. The struct...

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Detalles Bibliográficos
Autores principales: Syrbu, S. A., Semeikin, A. S., Lebedeva, N. Sh., Gubarev, Yu. A., Yurina, E. S., Guseinov, S. S., Koifman, O. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762635/
https://www.ncbi.nlm.nih.gov/pubmed/36569660
http://dx.doi.org/10.1007/s11172-022-3679-8