Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway

OBJECTIVES: To explore the anti-inflammatory effect and the potential mechanism of dexmedetomidine in ARDS/ALI. MATERIALS AND METHODS: C57BL/6 mice and EL-4 cells were used in this research. The ALI model was established by CLP. The level of inflammatory cytokines in the lung and blood, the severity...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng-tao, Xie, Ke, Luo, Ren-jie, Zhang, Dan-ying, He, Zhi-wei, Li, Ke-feng, Lin, Shi-hui, Xu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762669/
https://www.ncbi.nlm.nih.gov/pubmed/36534240
http://dx.doi.org/10.1007/s10787-022-01117-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762669/
https://www.ncbi.nlm.nih.gov/pubmed/36534240
http://dx.doi.org/10.1007/s10787-022-01117-5

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