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Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity

CRISPR-Cas systems are a family of adaptive immune systems that use small CRISPR RNAs (crRNAs) and CRISPR-associated (Cas) nucleases to protect prokaryotes from invading plasmids and viruses (i.e., phages). Type III systems launch a multilayered immune response that relies upon both Cas and non-Cas...

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Detalles Bibliográficos
Autores principales: Chou-Zheng, Lucy, Hatoum-Aslan, Asma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762709/
https://www.ncbi.nlm.nih.gov/pubmed/36479971
http://dx.doi.org/10.7554/eLife.81897