Apolipoprotein A1 Protects Against Necrotic Core Development in Atherosclerotic Plaques: PDZK1-Dependent High-Density Lipoprotein Suppression of Necroptosis in Macrophages

Atherosclerosis is a chronic disease affecting artery wall and a major contributor to cardiovascular diseases. Large necrotic cores increase risk of plaque rupture leading to thrombus formation. Necrotic cores are rich in debris from dead macrophages. Programmed necrosis (necroptosis) contributes to...

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Detalles Bibliográficos
Autores principales: Kluck, George E.G., Qian, Alexander S., Sakarya, Emmanuel H., Quach, Henry, Deng, Yak D., Trigatti, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762725/
https://www.ncbi.nlm.nih.gov/pubmed/36353992
http://dx.doi.org/10.1161/ATVBAHA.122.318062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762725/
https://www.ncbi.nlm.nih.gov/pubmed/36353992
http://dx.doi.org/10.1161/ATVBAHA.122.318062

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