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Low- and high-cocaine intake affects the spatial and temporal dynamics of class IIa HDAC expression-activity in the nucleus accumbens and hippocampus of male rats as measured by [18F]TFAHA PET/CT neuroimaging

Repeated cocaine alters neuronal function in the nucleus accumbens (NAc), a brain region involved in cocaine taking, and in hippocampus (HC), known for contextual and associative learning. [(18)F]TFAHA is a histone deacetylase (HDAC) class IIa-specific radiotracer for positron emission tomography (P...

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Detalles Bibliográficos
Autores principales: Perrine, Shane A., Alsharif, Walid F., Harutyunyan, Arman, Kamal, Swatabdi, Viola, Nerissa T., Gelovani, Juri G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762729/
https://www.ncbi.nlm.nih.gov/pubmed/36540409
http://dx.doi.org/10.1016/j.addicn.2022.100046