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Low- and high-cocaine intake affects the spatial and temporal dynamics of class IIa HDAC expression-activity in the nucleus accumbens and hippocampus of male rats as measured by [18F]TFAHA PET/CT neuroimaging
Repeated cocaine alters neuronal function in the nucleus accumbens (NAc), a brain region involved in cocaine taking, and in hippocampus (HC), known for contextual and associative learning. [(18)F]TFAHA is a histone deacetylase (HDAC) class IIa-specific radiotracer for positron emission tomography (P...
Autores principales: | Perrine, Shane A., Alsharif, Walid F., Harutyunyan, Arman, Kamal, Swatabdi, Viola, Nerissa T., Gelovani, Juri G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762729/ https://www.ncbi.nlm.nih.gov/pubmed/36540409 http://dx.doi.org/10.1016/j.addicn.2022.100046 |
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