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SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

BACKGROUND: Most studies of immunity to SARS-CoV-2 focus on circulating antibody, giving limited insights into mucosal defences that prevent viral replication and onward transmission. We studied nasal and plasma antibody responses one year after hospitalisation for COVID-19, including a period when...

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Detalles Bibliográficos
Autores principales: Liew, Felicity, Talwar, Shubha, Cross, Andy, Willett, Brian J., Scott, Sam, Logan, Nicola, Siggins, Matthew K., Swieboda, Dawid, Sidhu, Jasmin K., Efstathiou, Claudia, Moore, Shona C., Davis, Chris, Mohamed, Noura, Nunag, Jose, King, Clara, Thompson, A.A. Roger, Rowland-Jones, Sarah L., Docherty, Annemarie B., Chalmers, James D., Ho, Ling-Pei, Horsley, Alexander, Raman, Betty, Poinasamy, Krisnah, Marks, Michael, Kon, Onn Min, Howard, Luke, Wootton, Daniel G., Dunachie, Susanna, Quint, Jennifer K., Evans, Rachael A., Wain, Louise V., Fontanella, Sara, de Silva, Thushan I., Ho, Antonia, Harrison, Ewen, Baillie, J. Kenneth, Semple, Malcolm G., Brightling, Christopher, Thwaites, Ryan S., Turtle, Lance, Openshaw, Peter J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762734/
https://www.ncbi.nlm.nih.gov/pubmed/36543718
http://dx.doi.org/10.1016/j.ebiom.2022.104402