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Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway

CONTEXT: Salvianolic acid B (SAB) can alleviate renal fibrosis and improve the renal function. OBJECTIVE: To investigate the effect of SAB on renal tubulointerstitial fibrosis and explore its underlying mechanisms. MATERIALS AND METHODS: Male C57 mice were subjected to unilateral ureteric obstructio...

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Detalles Bibliográficos
Autores principales: Lin, Pinglan, Qiu, Furong, Wu, Ming, Xu, Lin, Huang, Di, Wang, Chen, Yang, Xuejun, Ye, Chaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762854/
https://www.ncbi.nlm.nih.gov/pubmed/36524761
http://dx.doi.org/10.1080/13880209.2022.2148169