Work-loop contractions reveal that the afterload-dependent time course of cardiac Ca(2+) transients is modulated by preload

Preload and afterload dictate the dynamics of the cyclical work-loop contraction that the heart undergoes in vivo. Cellular Ca(2+) dynamics drive contraction, but the effects of afterload alone on the Ca(2+) transient are inconclusive. To our knowledge, no study has investigated whether the putative...

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Detalles Bibliográficos
Autores principales: Dowrick, Jarrah M., Tran, Kenneth, Garrett, Amy S., Anderson, Alex J., Nielsen, Poul M. F., Taberner, Andrew J., Han, June-Chiew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762964/
https://www.ncbi.nlm.nih.gov/pubmed/35771221
http://dx.doi.org/10.1152/japplphysiol.00137.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762964/
https://www.ncbi.nlm.nih.gov/pubmed/35771221
http://dx.doi.org/10.1152/japplphysiol.00137.2022

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