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Work-loop contractions reveal that the afterload-dependent time course of cardiac Ca(2+) transients is modulated by preload
Preload and afterload dictate the dynamics of the cyclical work-loop contraction that the heart undergoes in vivo. Cellular Ca(2+) dynamics drive contraction, but the effects of afterload alone on the Ca(2+) transient are inconclusive. To our knowledge, no study has investigated whether the putative...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Physiological Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762964/ https://www.ncbi.nlm.nih.gov/pubmed/35771221 http://dx.doi.org/10.1152/japplphysiol.00137.2022 |