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Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model

Although the link of white matter to pathophysiology of schizophrenia is documented, loss of myelin is not detected in patients at the early stages of the disease, suggesting that pathological evolution of schizophrenia may occur before significant myelin loss. Disrupted-in-schizophrenia-1 (DISC1) p...

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Detalles Bibliográficos
Autores principales: Yu, Guangdan, Su, Yixun, Guo, Chen, Yi, Chenju, Yu, Bin, Chen, Hui, Cui, Yihui, Wang, Xiaorui, Wang, Yuxin, Chen, Xiaoying, Wang, Shouyu, Wang, Qi, Chen, Xianjun, Hu, Xuelian, Mei, Feng, Verkhratsky, Alexei, Xiao, Lan, Niu, Jianqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763102/
https://www.ncbi.nlm.nih.gov/pubmed/36131044
http://dx.doi.org/10.1038/s41380-022-01777-3