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Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model
Although the link of white matter to pathophysiology of schizophrenia is documented, loss of myelin is not detected in patients at the early stages of the disease, suggesting that pathological evolution of schizophrenia may occur before significant myelin loss. Disrupted-in-schizophrenia-1 (DISC1) p...
Autores principales: | Yu, Guangdan, Su, Yixun, Guo, Chen, Yi, Chenju, Yu, Bin, Chen, Hui, Cui, Yihui, Wang, Xiaorui, Wang, Yuxin, Chen, Xiaoying, Wang, Shouyu, Wang, Qi, Chen, Xianjun, Hu, Xuelian, Mei, Feng, Verkhratsky, Alexei, Xiao, Lan, Niu, Jianqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763102/ https://www.ncbi.nlm.nih.gov/pubmed/36131044 http://dx.doi.org/10.1038/s41380-022-01777-3 |
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