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Independent replication of advanced brain age in mild cognitive impairment and dementia: detection of future cognitive dysfunction

We previously developed a novel machine-learning-based brain age model that was sensitive to amyloid. We aimed to independently validate it and to demonstrate its utility using independent clinical data. We recruited 650 participants from South Korean memory clinics to undergo magnetic resonance ima...

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Detalles Bibliográficos
Autores principales: Karim, Helmet T., Aizenstein, Howard J., Mizuno, Akiko, Ly, Maria, Andreescu, Carmen, Wu, Minjie, Hong, Chang Hyung, Roh, Hyun Woong, Park, Bumhee, Lee, Heirim, Kim, Na-Rae, Choi, Jin Wook, Seo, Sang Won, Choi, Seong Hye, Kim, Eun-Joo, Kim, Byeong C., Cheong, Jae Youn, Lee, Eunyoung, Lee, Dong-gi, Cho, Yong Hyuk, Moon, So Young, Son, Sang Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763106/
https://www.ncbi.nlm.nih.gov/pubmed/35974140
http://dx.doi.org/10.1038/s41380-022-01728-y