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Pharmacokinetics and tolerability of intranasal or intravenous administration of nalbuphine in infants

OBJECTIVES: Intranasal nalbuphine could be a safe, efficacious and non-invasive alternative to parenteral pain medication in infants. We aimed to assess pharmacokinetics (PK) and tolerability of intranasal and intravenous nalbuphine administration in infants. METHODS: Prospective open-label study in...

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Detalles Bibliográficos
Autores principales: Pfiffner, Miriam, Gotta, Verena, Pfister, Marc, Vonbach, Priska, Berger-Olah, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763164/
https://www.ncbi.nlm.nih.gov/pubmed/36100355
http://dx.doi.org/10.1136/archdischild-2022-323807