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Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
OBJECTIVE: Idiopathic Parkinson’s disease (PD) is characterised by alpha-synuclein (aSyn) aggregation and death of dopaminergic neurons in the midbrain. Recent evidence posits that PD may initiate in the gut by microbes or their toxins that promote chronic gut inflammation that will ultimately impac...
Autores principales: | Esteves, A Raquel, Munoz-Pinto, Mário F, Nunes-Costa, Daniela, Candeias, Emanuel, Silva, Diana F, Magalhães, João D, Pereira-Santos, A Raquel, Ferreira, I Luisa, Alarico, Susana, Tiago, Igor, Empadinhas, Nuno, Cardoso, Sandra Morais |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763194/ https://www.ncbi.nlm.nih.gov/pubmed/34836918 http://dx.doi.org/10.1136/gutjnl-2021-326023 |
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