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In-depth analysis of alternative splicing landscape in multiple myeloma and potential role of dysregulated splicing factors

Splicing changes are common in cancer and are associated with dysregulated splicing factors. Here, we analyzed RNA-seq data from 323 newly diagnosed multiple myeloma (MM) patients and described the alternative splicing (AS) landscape. We observed a large number of splicing pattern changes in MM cell...

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Detalles Bibliográficos
Autores principales: Aktas Samur, Anil, Fulciniti, Mariateresa, Avet-Loiseau, Herve, Lopez, Michael A., Derebail, Sanika, Corre, Jill, Minvielle, Stephane, Magrangeas, Florence, Moreau, Philippe, Anderson, Kenneth C., Parmigiani, Giovanni, Samur, Mehmet K., Munshi, Nikhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763261/
https://www.ncbi.nlm.nih.gov/pubmed/36535935
http://dx.doi.org/10.1038/s41408-022-00759-6