Natural killer cells induce HIV-1 latency reversal after treatment with pan-caspase inhibitors

The establishment of a latency reservoir is the major obstacle for a cure of HIV-1. The shock-and-kill strategy aims to reactivate HIV-1 replication in HIV -1 latently infected cells, exposing the HIV-1-infected cells to cytotoxic lymphocytes. However, none of the latency reversal agents (LRAs) test...

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Detalles Bibliográficos
Autores principales: Furtado Milão, Joana, Love, Luca, Gourgi, George, Derhaschnig, Lukas, Svensson, J. Peter, Sönnerborg, Anders, van Domselaar, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763267/
https://www.ncbi.nlm.nih.gov/pubmed/36561752
http://dx.doi.org/10.3389/fimmu.2022.1067767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763267/
https://www.ncbi.nlm.nih.gov/pubmed/36561752
http://dx.doi.org/10.3389/fimmu.2022.1067767

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