Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment

This study examined the role of sirtuins in the regenerative potential of articular chondrocytes. Sirtuins (SIRT1-7) play a key role in regulating cartilage homeostasis. By inhibiting pro-inflammatory pathways responsible for cartilage degradation and promoting the expression of key matrix component...

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Detalles Bibliográficos
Autores principales: Heywood, Hannah K., Thorpe, Stephen D., Jeropoulos, Renos M., Caton, Paul W., Lee, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763269/
https://www.ncbi.nlm.nih.gov/pubmed/36561039
http://dx.doi.org/10.3389/fbioe.2022.971932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763269/
https://www.ncbi.nlm.nih.gov/pubmed/36561039
http://dx.doi.org/10.3389/fbioe.2022.971932

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