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Hedgehog-mediated gut-taste neuron axis controls sweet perception in Drosophila

Dietary composition affects food preference in animals. High sugar intake suppresses sweet sensation from insects to humans, but the molecular basis of this suppression is largely unknown. Here, we reveal that sugar intake in Drosophila induces the gut to express and secrete Hedgehog (Hh) into the c...

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Detalles Bibliográficos
Autores principales: Zhao, Yunpo, Khallaf, Mohammed A., Johansson, Emilia, Dzaki, Najat, Bhat, Shreelatha, Alfredsson, Johannes, Duan, Jianli, Hansson, Bill S., Knaden, Markus, Alenius, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763350/
https://www.ncbi.nlm.nih.gov/pubmed/36535958
http://dx.doi.org/10.1038/s41467-022-35527-4