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Distinct VSV-based Nipah virus vaccines expressing either glycoprotein G or fusion protein F provide homologous and heterologous protection in a nonhuman primate model

BACKGROUND: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority. METHODS: We produced two NiV vaccine candidates using the licensed VSV-EB...

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Detalles Bibliográficos
Autores principales: de Wit, Emmie, Feldmann, Friederike, Cronin, Jacqueline, Goldin, Kerry, Mercado-Hernandez, Reinaldo, Williamson, Brandi N., Meade-White, Kimberly, Okumura, Atsushi, Callison, Julie, Weatherman, Sarah, Rosenke, Rebecca, Avanzato, Victoria A., Lovaglio, Jamie, Scott, Dana P., Marzi, Andrea, Feldmann, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763366/
https://www.ncbi.nlm.nih.gov/pubmed/36508878
http://dx.doi.org/10.1016/j.ebiom.2022.104405