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Distinct VSV-based Nipah virus vaccines expressing either glycoprotein G or fusion protein F provide homologous and heterologous protection in a nonhuman primate model
BACKGROUND: Nipah virus (NiV) causes recurrent outbreaks of lethal respiratory and neurological disease in Southeast Asia. The World Health Organization considers the development of an effective vaccine against NiV a priority. METHODS: We produced two NiV vaccine candidates using the licensed VSV-EB...
Autores principales: | de Wit, Emmie, Feldmann, Friederike, Cronin, Jacqueline, Goldin, Kerry, Mercado-Hernandez, Reinaldo, Williamson, Brandi N., Meade-White, Kimberly, Okumura, Atsushi, Callison, Julie, Weatherman, Sarah, Rosenke, Rebecca, Avanzato, Victoria A., Lovaglio, Jamie, Scott, Dana P., Marzi, Andrea, Feldmann, Heinz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763366/ https://www.ncbi.nlm.nih.gov/pubmed/36508878 http://dx.doi.org/10.1016/j.ebiom.2022.104405 |
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