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Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance

The accumulation of α-synuclein (α-syn) in intracellular formations known as Lewy bodies (LBs) is associated with several neurodegenerative diseases including Parkinson’s disease and Lewy Body Dementia. There is still limited understanding of how α-syn and LB formation is associated with cellular dy...

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Detalles Bibliográficos
Autores principales: Croft, Cara L., Paterno, Giavanna, Vause, Ava R., Rowe, Lyla A., Ryu, Daniel H., Goodwin, Marshall S., Moran, Corey A., Cruz, Pedro E., Giasson, Benoit I., Golde, Todd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763367/
https://www.ncbi.nlm.nih.gov/pubmed/36535953
http://dx.doi.org/10.1038/s41531-022-00434-4