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Embryonic organizer formation disorder leads to multiorgan dysplasia in Down syndrome

Despite the high prevalence of Down syndrome (DS) and early identification of the cause (trisomy 21), its molecular pathogenesis has been poorly understood and specific treatments have consequently been practically unavailable. A number of medical conditions throughout the body associated with DS ha...

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Detalles Bibliográficos
Autores principales: Liu, Yanyan, Lin, Ziyuan, Peng, Ying, Jiang, Yan, Zhang, Xuan, Zhu, Hongmei, Zhang, Lili, Chen, Jiurong, Shu, Xianghua, Luo, Min, Xie, Dan, Chen, Yan, Liao, Huijuan, Liu, Mingfeng, Zhang, Xiaohu, Liu, Shanling, Wang, He, Zhou, Bin, Sun, Huaqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763398/
https://www.ncbi.nlm.nih.gov/pubmed/36535930
http://dx.doi.org/10.1038/s41419-022-05517-x