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Stabilization of MCL-1 by E3 ligase TRAF4 confers radioresistance

The E3 ligase TNF receptor-associated factor 4 (TRAF4) is frequently overexpressed and closely related to poor prognosis in human malignancies. However, its effect on carcinogenesis and radiosensitivity in oral squamous cell carcinoma (OSCC) remains unclear. The present study found that TRAF4 was si...

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Detalles Bibliográficos
Autores principales: Li, Ming, Gao, Feng, Li, Xiaoying, Gan, Yu, Han, Shuangze, Yu, Xinfang, Liu, Haidan, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763423/
https://www.ncbi.nlm.nih.gov/pubmed/36535926
http://dx.doi.org/10.1038/s41419-022-05500-6