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A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits

Identifying genomic regions pertinent to complex traits is a common goal of genome-wide and epigenome-wide association studies (GWAS and EWAS). GWAS identify causal genetic variants, directly or via linkage disequilibrium, and EWAS identify variation in DNA methylation associated with a trait. While...

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Detalles Bibliográficos
Autores principales: Battram, Thomas, Gaunt, Tom R., Relton, Caroline L., Timpson, Nicholas J., Hemani, Gibran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763500/
https://www.ncbi.nlm.nih.gov/pubmed/36535946
http://dx.doi.org/10.1038/s41467-022-35037-3