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DAB2IP attenuates chemoresistance of triple‐negative breast cancer through sequestration of RAC1 to prevent β‐catenin nuclear accumulation

BACKGROUND: Although chemotherapy, the most widely used systemic treatment in triple‐negative breast cancer (TNBC), markedly improved the patients’ outcome, chemoresistance always occurs. This study purposed to explore new therapeutic strategies for the treatment of chemoresistance. METHODS AND RESU...

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Detalles Bibliográficos
Autores principales: Xiong, Zhenchong, Yang, Lin, Li, Ning, Fu, Jianchang, Liu, Peng, Sun, Peng, Wei, Weidong, Xie, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763535/
https://www.ncbi.nlm.nih.gov/pubmed/36536485
http://dx.doi.org/10.1002/ctm2.1133