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Multi‐omics integration reveals a core network involved in host defence and hyperkeratinization in psoriasis

OBJECTIVES: The precise pathogenesis of psoriasis remains incompletely explored. We aimed to better understand the underlying mechanisms of psoriasis, using a systems biology approach based on transcriptomics and microbiome profiling. METHODS: We collected the skin tissue biopsies and swabs in both...

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Detalles Bibliográficos
Autores principales: Deng, Jingwen, Leijten, Emmerik, Nordkamp, Michel Olde, Zheng, Guangjuan, Pouw, Juliëtte, Tao, Weiyang, Hartgring, Sarita, Balak, Deepak, Rijken, Rianne, Huang, Runyue, Radstake, Timothy, Lu, Chuanjian, Pandit, Aridaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763538/
https://www.ncbi.nlm.nih.gov/pubmed/36536476
http://dx.doi.org/10.1002/ctm2.976