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Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing

Cartwheel assembly is considered the first step in the initiation of procentriole biogenesis; however, the reason for persistence of the assembled human cartwheel structure from S phase to late mitosis remains unclear. Here, we demonstrate mainly using cell synchronization, RNA interference, immunof...

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Detalles Bibliográficos
Autores principales: Huang, Fan, Xu, Xiaowei, Xin, Guangwei, Zhang, Boyan, Jiang, Qing, Zhang, Chuanmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763691/
https://www.ncbi.nlm.nih.gov/pubmed/36356903
http://dx.doi.org/10.1016/j.jbc.2022.102658