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A hybrid nanoassembly for ultrasound-inducible cytosolic siRNA delivery and cancer sono-gene therapy

Cancer gene therapy by small-interfering RNAs (siRNAs) holds great promise but is impeded by a low cytoplasmic delivery efficiency. The past two decades have witnessed many efforts that are dedicated to discover biomaterials in order to increase cellular uptake efficiency of siRNAs. However, less at...

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Detalles Bibliográficos
Autores principales: Li, Gaigai, Zhang, Yan, Li, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9763732/
https://www.ncbi.nlm.nih.gov/pubmed/36512940
http://dx.doi.org/10.1016/j.ultsonch.2022.106262